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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLK
All Species:
33.33
Human Site:
T447
Identified Species:
52.38
UniProt:
Q9UBE8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBE8
NP_057315
527
58283
T447
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Chimpanzee
Pan troglodytes
XP_001147662
515
57030
T435
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Rhesus Macaque
Macaca mulatta
XP_001105594
573
63821
T435
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Dog
Lupus familis
XP_854001
515
57044
T435
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O54949
527
58294
T447
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506943
489
54907
T409
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Chicken
Gallus gallus
XP_415915
515
57031
T435
K
C
C
F
S
T
S
T
G
R
V
Y
T
S
D
Frog
Xenopus laevis
Q8QGV6
447
50120
T382
A
D
F
E
P
T
A
T
N
R
F
D
D
S
Y
Zebra Danio
Brachydanio rerio
XP_691913
533
58862
S453
K
C
C
Y
T
T
S
S
G
R
V
Y
T
S
D
Tiger Blowfish
Takifugu rubipres
NP_001027920
443
50497
P377
D
F
E
P
V
T
N
P
K
F
D
D
G
F
E
Fruit Fly
Dros. melanogaster
NP_729316
430
48177
P365
F
E
P
S
A
G
Q
P
F
D
D
L
W
E
R
Honey Bee
Apis mellifera
XP_394432
462
51375
G381
T
C
C
Y
T
T
S
G
G
L
R
Q
Y
T
G
Nematode Worm
Caenorhab. elegans
Q9U9Y8
634
71758
N551
S
C
C
Y
T
K
P
N
M
P
S
R
L
F
A
Sea Urchin
Strong. purpuratus
XP_780259
503
56057
C407
Q
G
N
T
V
P
L
C
I
N
P
Q
S
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39027
368
42280
D303
L
Q
R
M
L
V
F
D
P
T
K
R
I
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.7
89
97.5
N.A.
99.8
N.A.
N.A.
76.6
96.5
66
94.5
79.5
64.3
63.3
46.5
61.1
Protein Similarity:
100
97.7
89.6
97.7
N.A.
99.8
N.A.
N.A.
78.7
96.7
73.8
95.8
81.9
73.8
73
57.7
71.9
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
26.6
80
6.6
0
33.3
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
33.3
100
20
6.6
53.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
7
0
0
0
0
0
0
7
14
% A
% Cys:
0
67
67
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
7
0
7
14
14
7
0
54
% D
% Glu:
0
7
7
7
0
0
0
0
0
0
0
0
0
7
7
% E
% Phe:
7
7
7
47
0
0
7
0
7
7
7
0
0
14
0
% F
% Gly:
0
7
0
0
0
7
0
7
60
0
0
0
7
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
54
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% K
% Leu:
7
0
0
0
7
0
7
0
0
7
0
7
7
0
0
% L
% Met:
0
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
7
7
7
7
0
0
0
0
0
% N
% Pro:
0
0
7
7
7
7
7
14
7
7
7
0
0
0
0
% P
% Gln:
7
7
0
0
0
0
7
0
0
0
0
14
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
60
7
14
0
0
7
% R
% Ser:
7
0
0
7
47
0
60
7
0
0
7
0
7
67
0
% S
% Thr:
7
0
0
7
20
74
0
54
0
7
0
0
54
7
0
% T
% Val:
0
0
0
0
14
7
0
0
0
0
54
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
54
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _